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Information about Pulmonary Hypertension


Pulmonary hypertension (PH) is a group of diseases characterized by high blood pressure in the arteries that connect the heart to the lungs. Patients with PH experience symptoms such as shortness of breath, dizziness and fatigue, depending on the severity of the disease. PH affects people of all ages, races and ethnic backgrounds but there are risk factors and diseases that make some people more susceptible. PH can be due to unknown causes (idiopathic) or as a consequence of several conditions including: scleroderma, lupus or other inflammatory diseases; heart, lung, liver, kidney and/or blood diseases and blood clots.

Types of Pulmonary Hypertension

  • PH originating at the pulmonary arteries (known as pulmonary arterial hypertension or PAH)
  • PH due to diseases of the heart (known as pulmonary venous hypertension or PVH)
  • PH due to lung diseases or due to low oxygen levels
  • PH due to clots in the pulmonary arteries (known as chronic thromboembolic pulmonary hypertension or CTEPH)

Treatments for Pulmonary Hypertension

At the UIHHSS PH program we provide all approved advanced pulmonary hypertension therapies, such as:

  • Intravenous epoprostenol (lex: Flolan and Veletri)
  • Intravenous
  • Subcutaneous and inhaled treprostinil (ex: Remodulin and Tyvaso)
  • Bosentan and ambrisentan (ex: Tracleer and Letairis)
  • Sildenafil and tadalafil (ex: Revatio and Adcirca)

*Patients also have the opportunity to participate in clinical trials testing new therapies for PH.