CAR T-Cell Therapy

UI Health is an approved treatment site for CAR (Chimeric Antigen Receptor) T-Cell Therapy. This is an FDA-approved therapy for treating specific types of lymphoma, leukemia, and multiple myeloma in patients who have not responded to previous cancer treatments. Studies have shown CAR-T cell therapy offers excellent results for people with specific blood cancers where previous treatments didn’t work. This therapy provides a new avenue for combating cancer, potentially leading to improved survival and quality of life. CAR-T cell therapy works by attacking and killing cancer in the body by adapting millions of your own immune system cells.

Who Can Receive This Treatment?

CAR-T Cell Therapy is not the same as a stem cell transplant or chemotherapy. CAR-T therapy may be a treatment option for:

  • Relapsed, refractory B-cell acute lymphoblastic leukemia
  • Relapsed, refractory B-cell Non-Hodgkin’s lymphoma
  • Relapsed, refractory mantle cell lymphoma
  • Relapsed, refractory follicular lymphoma
  • Relapsed, refractory multiple myeloma

How it Works

CAR-T therapy works by:

  • Extracting T-cells or white blood cells from your blood
  • Modifying and duplicating T-cells in the lab
  • Reintroducing CAR-T cells back into your body where they will travel throughout the body looking for cancer cells
  • Millions of CAR-T cells detect and kill cancer cells
  • Most people have a reaction to CAR-T cells that requires them to stay in the hospital for days to weeks for monitoring and management.